Avalide is an effective medicine which aim is to lower the blood pressure. Hypertension provokes serious diseases as strokes, heart attack, and problems with the kidney. An angiotensin receptor blocker and diuretic are the basic components of the drug. The first one relaxes the walls of the blood vessels letting the blood move freely without the pressure. The second component stimulates urination so that a patient can get rid of extra salt and water which also provoke high blood pressure.
| Package | Per pill | Total price | Save | Order |
|---|---|---|---|---|
| 162.5mg x 30 Pills | $2.22 | $66.71 + Bonus - 4 Pills | - | Add to cart |
| 162.5mg x 60 Pills | $1.67 | $100.40 + Bonus - 4 Pills | $33.00 | Add to cart |
| 162.5mg x 90 Pills | $1.49 | $134.09 + Bonus - 7 Pills | $65.70 | Add to cart |
| 162.5mg x 120 Pills | $1.40 | $167.78 + Bonus - 7 Pills | $98.40 | Add to cart |
| 162.5mg x 180 Pills | $1.31 | $235.16 + Bonus - 11 Pills Free Trackable Delivery | $163.80 | Add to cart |
| 162.5mg x 270 Pills | $1.25 | $336.23 + Bonus - 11 Pills Free Trackable Delivery | $261.90 | Add to cart |
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The pills are prescribed for the treatment of hypertension and nephropathy, hypertension. They also help in the treatment of diabetes as part of combined antihypertensive therapy.
Product Description
The pills block the receptors of angiotensin, eliminating the effect which narrows blood vessels and the concentration of aldosterone in plasma. The pills act gradually. The maximum result comes in three to six hours after taking them. The effect of the drugs is maintained throughout the day. If you take the pills regularly, the effect would become stable after 2 weeks and after 4 to 6 weeks it would reach the highest level. The medication is very quickly and completely absorbed from the gastrointestinal tract. The speed of absorption is independent of food intake. Bioavailability of tablets is 60-80 %.
There is a direct connection between the dose of tablets and the concentration of its components in the blood The same concentration in plasma is achieved three days after the first dose of medication. They bind to proteins in 96%. The volume of distribution is 53-93 l, total Cl is 157-176 ml/min, of kidney Cl — 3-3,5 ml/min. When the drug was introduced in very high doses to animals (more than 500 mg a day), there were degenerative changes in the kidney, for example:
● Tubular extensions of renal tubules;
● High concentration of uric acid;
● Low renal perfusion.
When the tablets were taken within 2 years (animal experiment) no carcinogenic effect was found. No other kinds of toxicity ( mutagenic or teratogenic) has been detected.
Safety Information
It is not desirable to take pills for people with high sensitivity to its components. One can not take the pills in conjunction with ACE inhibitors. The medicine is not recommended if you have lactose intolerance ( hereditary, lactase deficiency, or poor glucose/galactose absorption). The pills are recommended to be taken during lactation and during pregnancy. The safety and efficacy of the remedy have not been studied for people under 18 years.
The pills are undesirable for people with renal insufficiency and with cardiomyopathy, during the treatment of diuretics, hemodialysis. You should stop taking the medicine if you are on a diet with a low amount of salt, with diarrhea and is more than 75 years old.
Side Effects
Adverse events of the drug were studied in more than 5,000 patients. Among them, there were 1300 patients with hypertension who took the drugs for more than six months and 400 patients who took the pills for one year or more. Undesirable effects were weak and quickly passed. Their frequency has not been associated with a high concentration of components of tablets in the blood. Adverse reactions emerging does not depend on age and sex. Pills may cause can cause the following violation in the respiratory system:
● A cough;
● Chest pain.
In the nervous system:
● Dizziness;
● A headache;
● Orthostatic vertigo.
● In the gastrointestinal tract and genitals:
● Diarrhea;
● Constipation;
● Heartburn;
● Vomiting;
● Nausea;
● Sexual dysfunction;
● High fatigue;
● Pain in a chest.
In the course of studies, such ghost effects were manifested in patients with nephropathy with type 2 diabetes - dizziness, orthostatic dizziness, orthostatic hypotension.
From the part of a biliary tract, there was a high activity of liver enzymes, jaundice, and hepatitis. In skeletal mice, the internal system and connective tissue. there was myalgia. Sometimes kidney failure developed.
Levitra - the main component - the active agent Vardenafil which promotes strengthening of blood circulation in generative organs of men. It allows to reach a high level erection at sexual stimulation, and also to increase sensitivity of head of a penis and to make sexual intercourse longer and more pleasant. The main feature of a drug Levitra - quickness of effect, duration of impact on an organism up to 12 hours and a very small number of side effects.
Cialis Soft Tabs differs from a usual tablet of Cialis in the fact that its action comes quicker. Cialis Soft is chewed and dissolved under a tongue that allows to reach a required effect in 10-15 minutes. Important!!! Cialis Soft is compatible to alcohol and greasy food!
Super ED Trial Pack (6 Viagra + 6 Cialis + 6 Levitra) - a set sampler of Super ED Trial Pack generics which was created at numerous requests of customers. The set comprises 6 tablets (of big popularity) for solution of men's intimate problems. The set consist of: Viagra 100 mg, Cialis (20 mg) and Levitra (20 mg) that is production of well known Indian companies. All medicine of the Super ED Trial Pack set contain optimum doses of active agent and therefore you can take it for several times. Besides, it is quite possible to save money, having divided each tablet into parts.
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Suprax - is a semisynthetic antibiotic of the group of the third generation cephalosporins for oral administration. It has bactericidal action. The drug is formed on the basis of cefiximum under the name Suprax given by such companies:Wyeth, Elder Pharmaceuticals, Fujisawa, Gedeon Richter, Hikma Pharmaceuticals, Lederle, Lupin Pharmaceuticals, Sanofi-Aventis.
Zerit - treatment of infection caused by HIV, with severe clinical manifestations and ineffectiveness or intolerance of zidovudine, and other antiretroviral drugs. The nucleoside analogue of thymidine is phosphorylated by cellular enzymes to its active form - stavudine triphosphate. Suppresses reverse transcriptase of HIV, cellular DNA polymerases (beta and gamma), inhibits the synthesis of viral and mitochondrial DNA. It is active against HIV-1.
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