Dapsone antibacterial agent, which is active concerning Mycobacterium leprae and tuberculosis. It has bacteriostatic action similar to antagonists of p-aminobenzoic acid.
| Package | Per pill | Total price | Save | Order |
|---|---|---|---|---|
| 100mg x 10 Pills | $4.95 | $49.48 + Bonus - 4 Pills | - | Add to cart |
| 100mg x 30 Pills | $3.53 | $105.80 + Bonus - 4 Pills | $42.60 | Add to cart |
| 100mg x 60 Pills | $3.17 | $190.27 + Bonus - 4 Pills | $106.80 | Add to cart |
| 100mg x 90 Pills | $3.05 | $274.75 + Bonus - 7 Pills Free Trackable Delivery | $171.00 | Add to cart |
| 100mg x 120 Pills | $2.99 | $359.22 + Bonus - 7 Pills Free Trackable Delivery | $235.20 | Add to cart |
Your order will be packed safe and secure and dispatched within 24 hours. This is exactly how your parcel will look like (pictures of a real shipping item). It has a size and a look of a regular private letter (9.4x4.3x0.3 inches or 24x11x0.7cm) and it does not disclose its contents
Dapsone product description
Dapsone is part of a group of substances called sulfones. The antibacterial result of Dapsone has the following mechanism, this substance, being a structural analog of para-aminobenzoic acid, interacts with dihydropyridine instead of para-aminobenzoic acid and competitively inhibits dihydropteroate synthetase. This prevents the synthesis of folic acid bacteria. Lack of folic acid, in turn, disrupts the formation of purines, pyrimidines and certain amino acids (methionine) of bacteria and, ultimately, leads to the cessation of bacterial growth. Dapsone has a bacteriostatic nature of the action, as it stops the growth and multiplication of bacteria, but does not cause their death.
Absorbed within 2-8 hours. It binds to plasma proteins by 70-90%, and the main metabolite of the drug - monoacetylldosone - by 99%. Metabolised in the liver to monoacetylldosone. Eliminated by the kidneys (70-85%) and through the gastrointestinal tract, 20% is excreted unchanged.
The drug is mainly used to treat leprosy and herpetiform dermatitis. During the treatment, it is necessary to perform a general blood test and monitor the liver transaminases, reticulocyte count, platelet count, methemoglobin concentration, urea nitrogen, creatinine. In addition, this medicine is designed for the treatment of tuberculosis, pneumonia caused by Pneumocystis carinii.
Dapsone safety information
The consumption of this medicine is oral. Dosing regimen is individual. As a part of combination therapy, this medical agent is used in a dosage of 50-100 mg/day or 1-2 mg/kg/day. If necessary, the maximum daily dosage is 300mg. The treatment procedure is long.
Among the contraindications, the manufacturer indicates hypersensitivity, incl. to sulfanilamides, a liver dysfunction, severe anemia, a deficiency of glucose-6-phosphate dehydrogenase or methemoglobin reductase (possibly the development of hemolytic anemia). The consumption of this medication during pregnancy and lactation is possible only for prevention therapy in patients with leprosy or herpetiform dermatitis.
Dapsone side effects
On the part of the blood: dose-dependent hemolysis with a growth in the level of hemoglobin and an growth in the amount of reticulocytes (in all patients), hemolytic anemia (pain in the back, legs, stomach area, loss of appetite, pallor of the skin, unusual fatigue or weakness, increase in body temperature), methemoglobinemia (cyanosis of the fingernails, lips or skin, shortness of breath, etc.), pathological changes in the blood (elevated body temperature, sore throat, unusual bleeding and hemorrhages, etc.), incl. agranulocytosis and hypoplastic anemia with fatal outcome, palpitation, cardialgia.
On the part of the skin: itching, dryness, redness or peeling of the skin, hair loss, toxic erythema, erythema multi-form, toxic epidermal necrolysis, nodular erythema, kore and scarlatina-like reactions.
On the part of the CNS and sensory organs: mental disorders, incl. mood changes, peripheral neuritis (sensation of numbness, tingling, burning, pain or weakness in the hands and feet), neurotoxicity (a headache, insomnia, nervousness).
On the part of allergic effects: skin rash, "sulphonic syndrome" (fever, malaise, exfoliative dermatitis, jaundice, lymphadenopathy, methemoglobinemia, anemia), usually develops after 6-8 weeks of therapy.
On the part of the digestive tract: liver damage (icterus sclera or skin), anorexia, nausea, vomiting.
Endep - tricyclic antidepressant. The mechanism of antidepressive action is connected with increase in concentration of noradrenaline in synapses and/or serotonin in CNS (decrease in return absorption). Accumulation of these neurotransmitters results from inhibition of their return capture by membranes of presynaptic neurons.
Cialis Professional - effective tablets for improvement of erection. They begin to work in 15 minutes from the moment of taking and actions for 36 hours. They can cause not less than 10, but no more than 16 erections. The medicine increases duration of sexual intercourse. The tablets are successfully used for reduction of time for recovery of erection after ejaculation.
Cialis Oral Jelly (Orange) - a new formula of Cialis which you can have, without washing down with water. Against background of ordinary drug it differs in increased influence speed. It is prescribed for improvement of sexual endurance of men during intimate proximity. It simplifies the excitative process of penis and strengthens erection. Noticeably increases duration of sexual intercourse. Besides, the drug possesses a pleasant orange flavor.
Flagyl - antiprotozoan and antimicrobic drug. It is prescribed at treatment of protozoan inspections (abenteric amebiasis, including amoebic abscess of liver, an intestinal amebiasis, trichomoniasis, giardiasis, balanthidiasis, lambliasis, skin leushmaniosis, mecotic vaginitis, mecotic urethritis), pseudomembranous colitis, gastritises, ulcer, prevention of postoperative complications (especially interventions at segmented intestine, perirectal area, appendectomy, gynecologic operations).
Floxin - antimicrobic broad-spectrum agent from group of fluroquinolone. It is active concerning the microorganisms producing beta lactamelements and fast-growing atypical mycobacteria. It is taken at respiratory infection, the ENT organs, skin, soft tissues, bones, joints, abdominal cavity, urinary tract.
Frumil - combined diuretic medicine which consists of AMILORIDE HYDROCHLORIDE ANHYDROUS and FRUSEMIDE which action is caused by its components; it has diuretic and hypotensive effect. Amiloride reduces egestion of K+ and Mg2+. FRUSEMIDE "looping" diuretic. The combination of components of a drug reduces a risk of development of hypopotassemia and hypomagnesiemia.
The drug dilates coronary vessels (mostly arterioles) and causes a significant increase in volumetric blood flow velocity. Increases the content of oxygen in venous blood of coronary sinus and its absorption by myocardium. Promotes the development of collateral coronary circulation, reduction in a systemic vascular resistance, improves microcirculation, has angioprotective action.
Ventolin is a medicament for eliminating asthma attacks (bronchial) and other reversible diseases with bronchial obstruction.
The main active substance is salbutamol.
Zerit - treatment of infection caused by HIV, with severe clinical manifestations and ineffectiveness or intolerance of zidovudine, and other antiretroviral drugs. The nucleoside analogue of thymidine is phosphorylated by cellular enzymes to its active form - stavudine triphosphate. Suppresses reverse transcriptase of HIV, cellular DNA polymerases (beta and gamma), inhibits the synthesis of viral and mitochondrial DNA. It is active against HIV-1.
Rizact -pills swallowed for the urgent care of the headache phase within the attacks of migraines. This Cipla product is a great painkillerthanks to an action of Rizatriptan, which is characterized by an analgesic effect.
Caverta - another affordable version of Indian Viagra created by Ranbaxy, released as Caverta 100mg and Caverta 50mg.
Avalide is an effective medicine which aim is to lower the blood pressure. Hypertension provokes serious diseases as strokes, heart attack, and problems with the kidney. An angiotensin receptor blocker and diuretic are the basic components of the drug. The first one relaxes the walls of the blood vessels letting the blood move freely without the pressure. The second component stimulates urination so that a patient can get rid of extra salt and water which also provoke high blood pressure.
Ciplox is a medicine which is antimicrobial of the fluoroquinolone group. The system of action is connected with exposure to DNA bacteria. The medicine eliminates microorganisms that are both at rest and reproduction. A range of action of the drug includes such types of negative and positive microorganisms: Shigella, Salmonella, Citrobacter, Klebsiella, Enterobacter, Serratia, Hafnia, Edwardsiella and others. It is resistant to Ureaplasma uralyticum, Nocardia asteroids, Treponema pallidum. Such defiance to the drug develops slowly and gradually.
It facilitates or eliminates the manifestations of a menopausal syndrome (feeling of heat, sweating, dizziness, irritability, depression), prevents the development of osteoporosis, normalizes the menstrual cycle in women of childbearing age, reduces the level of testosterone in men. The medicine regulates the development and preservation of the function of the female reproductive system, the formation of secondary sexual characteristics.It relieves or stops manifestations of irritability, anxiety, depression, and urogenital ( progressive diffuse atrophy of the external genitals) symptoms.
Synthroid finds use as a hormone-regulating agent for managing low levels of triiodothyronine/thyroxine. It also has a pronounced therapeutic effect on goiters of certain types. Synthroid often accompanies surgeries and other medical means of treating thyroid cancer. The drug compensates for the insufficient production of thyroid hormones by standing in their place as a synthetic substitution. Compensations of this kind help the patient’s body to restitute the normal rate of metabolism. Synthroid also helps to fight obesity due to its ability to remove the initial thyroid gland-related causes as such.
