An antiparkinsonian agent. A non-ergoline selective agonist of dopamine D2 and D3 receptors. A possible mechanism of action in the treatment of Parkinson's disease , associated with a stimulating effect on the postsynaptic D2 receptors of the basal nuclei in the brain.
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Requip Product Description
Drug Uses
Requip is a non-ergoline dopamine agonist, stimulating striatal dopamine receptors and improving the chemical imbalance in the brain affected by Parkinson's disease. This drug provides an effect in the hypothalamus and pituitary by inhibiting the prolactin secretion.
Requip is indicated to adults for treatment of Parkinson's disease symptoms as monotherapy or in combination with levodopa. The application of the antiparkinson drug can delay administration of levodopa.
In addition, Requip may also be administered for treatment of moderate-to-severe primary restless legs syndrome. This neurological disorder is characterized by unpleasant sensations in the legs, often appearing during the night.
An initial recommended dose of Requip is 0.75 mg per day (one 0.25 mg tablet of Requip three times a day) for 7 days. Then the daily dose is to be increased, taking into account the tolerance to the antiparkinson drug and the therapeutic response. The maximum Requip dose should not exceed 24 mg per day.
Missed Dose
If the patient had missed the dose of Requip, s/he must skip the tablet in case if it is close to the next scheduled dose of this antiparkinsonian agent. If it is enough time till the next dose of Requip, the patient can use a tablet immediately as it possible.
More Information
When Requip is prescribed as an adjunct to levodopa therapy, the daily dose of levodopa is recommended to be reduced. This will help avoid excessive dopamine stimulation and development of side effects. Levodopa dosage should be decreased gradually.
Storage
Recommended temperature for Requip storage is from 20°C to 25°C. Keep the tablets in a warm dry place in a tightly closed bottle.
Requip Safety Information
Warnings
Requip may cause sudden sleep attacks and daytime sleepiness. The patients feeling sleepy should be advised not to drive a motor vehicle or operate machinery. In order to reduce the risk of sudden sleep attacks, the daily dose of the antiparkinson drug should be decreased. If cases of sudden onset of sleep are failed to be minimized, it is recommended to stop taking Requip and to consider alternative treatments for Parkinson's disease.
Disclaimer
All the information about Parkinson's Disease, which is included in the review of Requip, is published for general information purpose only, and should not be taken as a substitute for professional advice of the qualified medical professional. The online pharmacy shall disclaim any responsibility for any kind of consequences, including damage or loss, which may follow from the use of information about antiparkinsonian agent, Requip.
Requip Side Effects
The most common adverse events, caused by Requip, include vomiting, heartburn, nausea, syncope, dizziness, abdominal pain, dyskinesia. They usually appear at the beginning of the treatment with the antiparkinsonian agent, are mild, and rarely result in withdrawal of Requip. Less commonly, the antiparkinsonian drug may cause other adverse events, such as leg edema, sweating, confusion, dyspepsia, hallucinations, viral infection, somnolence, headache or asthenic condition. The intensity and frequency of Requip adverse events can be reduced by lowering the dose.
Abilify is designed for patients with diagnosis named schizophrenia. It is used either during the exacerbation period or for maintenance treatment. Abilify is also prescribed in cases of an acute manic episodes of type 1 in manic-depressive psychosis, and as a supportive treatment for bipolar affective disorders. Abilify can be used as an additional treatment during depressive disorders. According to some experts, the drug can be used in order to treat alcoholism.
Cialis Professional - effective tablets for improvement of erection. They begin to work in 15 minutes from the moment of taking and actions for 36 hours. They can cause not less than 10, but no more than 16 erections. The medicine increases duration of sexual intercourse. The tablets are successfully used for reduction of time for recovery of erection after ejaculation.
Super ED Trial Pack (6 Viagra + 6 Cialis + 6 Levitra) - a set sampler of Super ED Trial Pack generics which was created at numerous requests of customers. The set comprises 6 tablets (of big popularity) for solution of men's intimate problems. The set consist of: Viagra 100 mg, Cialis (20 mg) and Levitra (20 mg) that is production of well known Indian companies. All medicine of the Super ED Trial Pack set contain optimum doses of active agent and therefore you can take it for several times. Besides, it is quite possible to save money, having divided each tablet into parts.
Aceon, which is perindopril - is prescribed at hypertensia, stroke prevention, chronic cardiac failure. Medicine has a vasorelaxant action, it reduces an afterload due to TPR relief, the medicine reduces resistance in vessels of lungs. It is observed increase of the minute volume of myocardium and increase tolerance of myocardium to strain. The medicine has the natriuretic effect and cardioprotection action. The effect of hypotension is observed in 60 minutes after taking the medicine. Arterial pressure loss isn't followed by development of tachycardia. The maximum therapeutic effect is observed in 4-8 hours, the effect is long-term (up to 24 hours). Perindopril improves brain, kidneys, and myocardium circulation, it reduces the needs of cardiomyocytes for oxygen at CHD.
Actonel, which is risedronate - is prescribed for treatment and prevention of osteoporosis (post-menopausal, caused by corticosteroids), Paget disease. Risedronate binds to substance of a bone tissue, inhibits its resorption mediated by osteoclasts and reduces a bone turn (does not break process of formation of a bone). It increases the biomechanical strength and volume of bone mass. The maximum decrease in a bone turn is observed in 3-6 months, remaining at the same level during a course of treatment.
Actos, which is pioglitazone - is prescribed to patients with diabetes of type 2 (both as monotherapy, and in a form of the combined therapy with sulphonylurea, metformin or insulin as additional medicine to dietotherapy and physical exercises). Pioglitazone represents peroral hypoglycemic medicine of Thiazolidinediones alignment which effect depends on insulin presence. It is a high-selective agonist of gamma receptors, activated by proliferator of peroxysom (PPAR-γ).
Arava - a basic medicine with antirheumatic effect. Action is happened due to active metabolite of leflunomid. It has the inhibiting action on degidrorotate-dehydrogenase. Taking the medicine the progression of rheumatoid arthritis is slowed down, it is stopped the affection of arthral layers. Development of therapeutic effect is observed in a month. Increase of effect is noted within half a year.
is given to patients for treating severe acne that do not respond to other medicines
Dapsone antibacterial agent, which is active concerning Mycobacterium leprae and tuberculosis. It has bacteriostatic action similar to antagonists of p-aminobenzoic acid.
Endep - tricyclic antidepressant. The mechanism of antidepressive action is connected with increase in concentration of noradrenaline in synapses and/or serotonin in CNS (decrease in return absorption). Accumulation of these neurotransmitters results from inhibition of their return capture by membranes of presynaptic neurons.
Exforge the combined antihypertensive which includes amlodipine and valastran. Valsartan - a specific blocker of AT1 receptors of angiotensin II. Amlodipin - calcium channel blocking agents of III generation, inhibits transmembrane receipt of Ca2+ in cardiomyocytes and smooth muscle cells of vessels, by weakening them.
Levaquin is used to treat infections of the lower respiratory tract, urinary tract, kidneys, skin, soft tissues, chronic bronchitis, acute sinusitis, chronic bacterial prostatitis and tuberculosis. The drug is a fluoroquinolone, a broad-spectrum antimicrobial bactericide. It blocks DNA gyrase and topoisomerase IV, disrupts supercoiling and cross-linking of DNA gaps, suppresses DNA synthesis, causes profound morphological changes in the cytoplasm, cell wall and bacterial membranes.
A symptomatic medication against vomiting and nausea of various origins. Used at vomiting caused by radiation therapy or cytotoxic drugs intake, hypotony and atony of the stomach and intestines, biliary dyskinesia, reflux esophagitis, flatulence, aggravation of gastric ulcer and duodenal gut, when performing contrast studies of the gastrointestinal tract. It reduces the moving activity of the esophagus, increases the tone of the lower esophageal sphincter, accelerates gastric emptying, and accelerates the movement of food through the small intestine without causing diarrhea. Stimulates the secretion of prolactin.
The drug dilates coronary vessels (mostly arterioles) and causes a significant increase in volumetric blood flow velocity. Increases the content of oxygen in venous blood of coronary sinus and its absorption by myocardium. Promotes the development of collateral coronary circulation, reduction in a systemic vascular resistance, improves microcirculation, has angioprotective action.
Antiemetic, which is a specific blocker of dopamine (D2) and serotonin receptors. It has antiemetic effect, eliminates nausea and hiccups. Reduces moving activity of the esophagus, increases the tone of the lower esophageal sphincter, accelerates gastric emptying and the movement of food through the small intestine without causing diarrhea. Stimulates the secretion of prolactin.
Ventolin is a medicament for eliminating asthma attacks (bronchial) and other reversible diseases with bronchial obstruction.
The main active substance is salbutamol.
Zerit - treatment of infection caused by HIV, with severe clinical manifestations and ineffectiveness or intolerance of zidovudine, and other antiretroviral drugs. The nucleoside analogue of thymidine is phosphorylated by cellular enzymes to its active form - stavudine triphosphate. Suppresses reverse transcriptase of HIV, cellular DNA polymerases (beta and gamma), inhibits the synthesis of viral and mitochondrial DNA. It is active against HIV-1.
Rizact -pills swallowed for the urgent care of the headache phase within the attacks of migraines. This Cipla product is a great painkillerthanks to an action of Rizatriptan, which is characterized by an analgesic effect.
Avalide is an effective medicine which aim is to lower the blood pressure. Hypertension provokes serious diseases as strokes, heart attack, and problems with the kidney. An angiotensin receptor blocker and diuretic are the basic components of the drug. The first one relaxes the walls of the blood vessels letting the blood move freely without the pressure. The second component stimulates urination so that a patient can get rid of extra salt and water which also provoke high blood pressure.
Differin is a white gel or cream. The drug is used to treat acne. It can also be used to combat comedones. Differin monotherapy is helpful in case of minor acne. For the treatment of severe and moderate degree of acne, the drug is used in conjunction with systemic drugs (antiandrogens, antibacterial agents). The drug is well tolerated. It rarely causes irritation, so its use is good even for those who have sensitive skin with acne. The gel is more suitable for oily skin and the cream suits better for dry skin.
The medicine belongs to the group of cardiac glycosides. The preparation obtained from the medicinal plants' Woolly Foxglove. It has the following actions: inotropic, vasodilator and moderate diuretic. The pills increase the concussive and systolic volume of the heart, increases the refractory period, reduces atrioventricular conduction, reduces the frequency of contractions of the heart muscle. In the case of stagnation in cardiovascular insufficiency, it has a pronounced vasodilating effect. Lanoxin has a mild diuretic effect, reduces the severity of edema. Overdosage may trigger an increase in the excitability of the myocardium, resulting in disturbances of heart rhythm.
