A selective calcium channel blockers; a derivative of dihydropyridine; has a vasodilating, antihypertensive, antianginal effect. Has a high selective activity against smooth muscle of the arterioles. Prescribed to the patients with hypertension, angina pectoris (voltage, vasospastic, unstable with the ineffectiveness of beta-blockers and nitrates), Raynaud's syndrome (as a symptomatic drug).
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Plendil Product Description
Drug Uses
Plendil is a calcium channel blocker, used to treat hypertension (high blood pressure). Antihypertensive drug Plendil relaxes the blood vessels, thus increasing the blood flow and lowwering the blood pressure.
Because Plendil has no effect on the venous smooth muscle, the antihypertensive drug does not cause orthostatic hypotension (colloquially as head rush).
Calcium channel blocker Plendil is prescribed to adults and elderly patients for treatment of hypertension and prophylaxis of chronic stable angina pectoris. To treat high blood pressure, an initial recommended Plendil dose is 5 mg per day.
Depending on the tolerability and the effect, the daily dose of Plendil can be increased up to 10mg or decreased to 2.5mg. If necessary, therapy with Plendil can be supported with another antihypertensive agent. The recommended maintenance Plendil dose is 5-10mg per day.
Missed dose
If more than 12 hours has passed after a missed dose of Plendil, do not take the calcium antagonist. In this case just return to the regular dosing schedule of Plendil.
More Information
Plendil is completely absorbed from the gastrointestinal tract and immediately provides an antihypertensive effect, which lasts about 2-5 hours. At the systematic application of antihypertensive agent Plendil, substantial control of blood pressure lasts for 24 hours. Plendil is well tolerated by the patients with renal transplant and requires no modification of the recommended dosage in patients with renal impairment.
Storage
Antihypertensive Plendil agent should be stored in a dark place in a tightly closed container, at room temperature not exceeding 25°C.
Plendil Safety Information
Warnings
Plendil is recommended to be indicated with caution to the hypertensive patients with heart failure. Coadministration of the calcium channel blocker with beta-adrenergic blocking agents is especially recommended to be avoided.
In some cases, the hypertension treatment in the patients with coronary artery disease may cause significant hypotension and result in myocardial ischaemia. Therefore, the level of blood pressure is recommended to be thoroughly monitored in these patients during the antihypertensive therapy with Plendil. Also the patients with a history of cerebrovascular insufficiency should be careful and try to avoid hypotension.
Disclaimer
This review of Plendil contains only general information on the hypertension treatment. This information in no case should be treated as medical advice from the cardiologist or other professional healthcare provider. The online pharmacy shall not be liable for any loss or damage, caused due to improper use of the information provided on antihypertensive agent Plendil.
Plendil Side Effects
Adverse effects after the application of Plendil are usually transient and decrease when dosages are decreased. Only about 6% of patients taking Plendil, have to discontinue the treatment due to blushing, ankle edema and headache. Other common and the most serious adverse effects after the use of Plendil are: nausea, dizziness, vomiting, weakness, palpitation, flush, gingival overgrowth, paraesthesia, low blood pressure, costiveness or paresthesia.
Levitra - the main component - the active agent Vardenafil which promotes strengthening of blood circulation in generative organs of men. It allows to reach a high level erection at sexual stimulation, and also to increase sensitivity of head of a penis and to make sexual intercourse longer and more pleasant. The main feature of a drug Levitra - quickness of effect, duration of impact on an organism up to 12 hours and a very small number of side effects.
Cialis Professional - effective tablets for improvement of erection. They begin to work in 15 minutes from the moment of taking and actions for 36 hours. They can cause not less than 10, but no more than 16 erections. The medicine increases duration of sexual intercourse. The tablets are successfully used for reduction of time for recovery of erection after ejaculation.
Super ED Trial Pack (6 Viagra + 6 Cialis + 6 Levitra) - a set sampler of Super ED Trial Pack generics which was created at numerous requests of customers. The set comprises 6 tablets (of big popularity) for solution of men's intimate problems. The set consist of: Viagra 100 mg, Cialis (20 mg) and Levitra (20 mg) that is production of well known Indian companies. All medicine of the Super ED Trial Pack set contain optimum doses of active agent and therefore you can take it for several times. Besides, it is quite possible to save money, having divided each tablet into parts.
Aciphex - the medicine, normalizing acidity of a stomach, inhibitor of a proton pomp. It is prescribed at gastroduodenal ulcer in the exacerbation phase, gastroesophageal reflux disease; states which are characterized by pathological hyper secretion including Zollinger-Ellison syndrome. In combination with bactericide - Helicobacter pylori eradication at patients with gastric ulcer or chronic gastritis; treatment and prevention of recurrence of an ulcer at patients with gastric ulcer related to Helicobacter pylori.
Buspar - a partial agonist of serotonin and dopamine receptors - it has anxiolytic effect. Unlike benzodiazines buspirone does not suppress psychomotor function, or causes its small suppression; in moderate doses does not exponentiate effect of alcohol. It does not render somnolent, relaxant or antiepileptic effect.
Cefixime is a medicine intended for the treatment of acute and chronic bronchitis, bacterial bronchitis, middle ear inflammation, pharyngitis and tonsillitis, bacterial infections of the urinary tract, cystitis, urethritis, pyelonephritis, cerivitis.
Cipro - the antimicrobic broad-spectrum agent derivative of fluroquinolone, suppresses bacterial DNA gyrase, breaks DNA synthesis, growth and division of bacteria; causes prominent morphological changes and fast death of a bacterial cell. It effects bactericidal at gram-negative organisms during a dormant period and deletion, on gram-positive microorganisms - only during deletion. During taking Cipro there is no parallel development of resistance to other antibiotics, which do not belong to group of inhibitors of a gyrase that does it highly effective in relation to bacteria which can be steady, for example to aminoglycosides, penicillin, cephalosporins, tetracyclines and many other antibiotics.
Dramamine is an antihistamine drug that reduces the effect of the natural chemical histamine in the body. Dramamine is used to treat or prevent the occurrence of nausea, vomiting, and dizziness associated with motion sickness.
"Loop" diuretic, used for edematous syndrome with CHF II-III st., liver cirrhosis, kidney disease; swelling of the lungs or brain; arterial hypertension, hypercalcemia. Causes a rapidly advancing, strong and short-term diuresis. Has natriuretic and chlororetic effects, increases the excretion of K +, Ca2 +, Mg2 +.
A thiazide diuretic of the average intensity, applied in arterial hypertension, edema syndrome of different origin, gestosis and diabetes insipidus. Reduces reabsorption of Na+ at the level of the Henle loop cortical segment, without affecting its segment lying in the medulla of the kidney that detects a weaker diuretic effect compared with furosemide.
A combined medication used for edema syndrome of various origins and arterial hypertension. The effect is due to the components in its composition; it has diuretic and hypotensive effect. Hydrochlorothiazide is a diuretic of average power action, increases the excretion of Na+, Cl-, K+, Mg2+, bicarbonate; keeps Ca2+, uric acid in the body. Amiloride decreases the excretion of K+ and Mg2+. The combination of the drug components reduces the risk of hypokalemia and hypomagnesemia development.
An antiarrhythmic Ia class drug, a blocker of the "fast" Na+ channels. It has a membrane stabilizing, anti-arrhythmic, hypotensive and m-anticholinergic action. In normally functioning sinus node it causes acceleration of the sinus rhythm due to the antimuscarinic effect.
The drug is used for treatment of infectious diseases such as community acquired pneumonia, exacerbation of chronic bronchitis, acute sinusitis, pharyngitis and skin infections. The active ingredient in Omnicef is cefdinir—a semi-synthetic cephalosporin broad-spectrum antibiotic of the third generation for oral administration. Like other cephalosporin antibiotics, cefdinir has a bactericidal action against susceptible organisms through the inhibition of synthesis of bacteria peptidoglycan cell walls by interfering with the final stage of transamination, required for cross-linking.
Sinemet - a combined remedy based on Levodopum + Carbidopum. In the treatment of Parkinson's syndrome and disease, Sinemet proved to be one of the most effective drug. The reviews are mostly positive, because it allows to reduce "inhibition" in patients who have been treated with other medications. For each patient, the dosage is selected individually, together with the frequency of admission.
Valtrex is an antiviral. The active substance - valaciclovir - penetrates into the affected cell, interacts with enzymes, is embedded in the DNA of the pathogen. It is active against Herpes Simplex, Cytomegalovirus, Varicella-Zoster, Epstein-Barr, HHV-6 (herpes simplex type 6).
Caverta - another affordable version of Indian Viagra created by Ranbaxy, released as Caverta 100mg and Caverta 50mg.
Eriacta is a potent and safe equivalent of Viagra, represented in the pharmaceutical niche by Ranbaxy Laboratories Limited. The consumption of the potency regulator named Eriacta eliminates erectile malady and permits one to conduct a rich sexual life.
It is a powerful tool which lowers cholesterol in the blood, strengthens blood vessels and fights parasites. Lasuna balances coronary function prevents the accumulation of cholesterol on the walls of the coronary arteries. The medicine stabilizes blood pressure levels. It regulates the level of lipids in plasma, the number of platelets in the blood, cholesterol and blood sugar and strengthens immunity. Strong antioxidant properties eliminate free radicals that cause an imbalance in the normal functioning of blood vessels, which should fully narrow and expand for their natural work.